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1 article(s) from Das, Prajwalita

Synthesis of fluoro-functionalized diaryl-λ³-iodonium salts and their cytotoxicity against human lymphoma U937 cells

Prajwalita Das,
Etsuko Tokunaga,
Hidehiko Akiyama,
Hiroki Doi,
Norimichi Saito and
Norio Shibata

Beilstein J. Org. Chem. 2018, 14, 364–372, doi:10.3762/bjoc.14.24

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Figure 1: Compounds used for the biological study.

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Figure 2: Compounds 1–4 induced cell death in U937 cells. Briefly, U937 cells (1 × 10⁴ cells/mL) were incubat...

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Scheme 1: Synthesis of pentafluoro-(2-iodophenyl)-λ⁶-sulfane (7).

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Scheme 2: Synthesis of unsymmetrical ortho-SF₅ diaryliodonium salts 3p, 4b, 5a and 6a.

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Figure 3: X-ray crystallographic structure of 3p drawn at 50% probability (CCDC 1573953).

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Figure 4: Ortho-SF₅ phenyl iodonium salts 3p and 5a and their structural components 7 and 9 induced cell deat...

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Figure 5: 3k, 3m and 3p induced cell death in AGLCL, a human normal B cell line. Briefly, AGLCL cells (1 × 10⁴...

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Published 07 Feb 2018

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Synthesis of fluoro-functionalized diaryl-λ3-iodonium salts and their cytotoxicity against human lymphoma U937 cells

Synthesis of fluoro-functionalized diaryl-λ³-iodonium salts and their cytotoxicity against human lymphoma U937 cells